Cancer Treatment
Researchers from Canada and the United States report details of new studies and findings in the area of cancer treatment
Published in Cancer Vaccine Week, August 7th, 2006
Study 1: Insulin-like growth factor binding protein-4 (IGFBP-4) is a novel antiangiogenic and antitumorigenic mediator secreted by dibutyryl cyclic AMP (DB-cAMP)-differentiated glioblastoma cells.
According to a study from Canada, "CAMP has been shown to reverse the transformed phenotype of various cancer cells. Human glioblastoma U87MG cells exposed to 500 micromolar dB-cAMP for six days showed reduced proliferation, attenuated invasiveness, and inability to induce angiogenic responses in human brain endothelial cells (HBECs) grown in Matrigel. VEGF was the...
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Source: Cancer Vaccine Week (2006-08-07)
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