Vaccines
Study data from University of Southampton, Cancer Sciences Division update knowledge of vaccines
Published in Cancer Vaccine Week, April 14th, 2008
Fresh data on vaccines are presented in the report 'Tapasin shapes immunodominance hierarchies according to the kinetic stability of peptide - MHC class I complexes.' "Peptide loading of MHC class I molecules involves multiple cofactors including tapasin. We showed previously in vitro that tapasin edits the peptide repertoire by favoring the binding of peptides with slow dissociation rates," researchers in Southampton, the United Kingdom report.
"Here, using tapasin-deficient mice and a DNA vaccine that primes directly, we confirm that tapasin establishes hierarchical responses in vivo according to peptide-MHC stability. In contrast, this hierarchy is lost when the...
Want to see the full article?
We're a pay-per-view site for premium content. If you'd like to purchase this article, it's only $3.00.
Welcome to NewsRx!
Learn more about a six-week, no-risk free trial of Cancer Vaccine Week
Source: Cancer Vaccine Week (2008-04-14)
More Articles from Cancer Vaccine Week
- Cancer Vaccines
Data from University of Washington provide new insights into cancer vaccines - Cancer Vaccines
ImQuest Publishes Results of Important Structure Activity Relationship Program on Dual Acting Pyrimidinediones - Cancer Vaccines
New cancer vaccines research reported from Kanazawa University, Medical Department - Cancer Vaccines
Reports from University of California add new data to research in cancer vaccines - Cancer Vaccines
Research from G.G.G. Donders and co-authors reveals new findings on cancer vaccines - Cancer Vaccines
Research results from C. Ho and co-authors update knowledge of cancer vaccines - More from this issue of Cancer Vaccine Week
NewsRx is Social
Follow us on your favorite social network by clicking on a button below:
Top Medical Newsletters
Awards
Best Health/Healthcare Content, 2012
Best Health/Healthcare Content, 2011
Best e-Business Site, 2010
Best e-Business Site, 2009
Best e-Business Site, 2008
Best e-Business Site, 2007
Best e-Business Site, 2006
Best Healthcare Content, 2005
Best Overall Internet Site, 2005
Best Interactive Site, 2005
Facts & Stats
NewsRx also is available at LexisNexis, Gale, ProQuest, Factiva, Dialog, Thomson Reuters, NewsEdge, and Dow Jones.
- Google 2010 PageRank: #2 Among Top Health News and Media Publications
- Google 2010 PageRank: #2 Among Top Science Publications in Biology/Physiology
- Google 2010 PageRank: #2 Among Top News and Media for the Business of Pharmaceuticals
- Amazon's Alexa 2010 PageRank: #2 News and Media Site for the Pharmaceutical Industry
