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Cancer Vaccines

Data on cancer vaccines reported by researchers at University of California, Division of Neurosurgery

Published in Cancer Vaccine Week, August 18th, 2008

Fresh data on cancer are presented in the report 'Anti-tumor activity and trafficking of self, tumor-specific T cells against tumors located in the brain.' "It is commonly believed that T cells have difficulty reaching tumors located in the brain due to the presumed 'immune privilege' of the central nervous system (CNS). Therefore, we studied the biodistribution and anti-tumor activity of adoptively transferred T cells specific for an endogenous tumor-associated antigen (TAA), gp100, expressed by tumors implanted in the brain," researchers in the United States report.

"Mice with pre-established intracranial (i.c.) tumors underwent total body irradiation (TBI) to induce...

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