Gene Delivery

Artificial Viruses to Provide a Safer Vector for In Vivo Gene Transfer

Published in Cancer Weekly, March 27th, 1995

French researchers work one step closer to developing artificial viruses as effective vectors for gene therapy for inherited and acquired diseases.

Jean-Serge Remy et al. remark that most current ongoing human gene therapy protocols rely on recombinant retroviral and adenoviral vehicles which have limited carrier capacity and the possibility of safety and immunological problems with large scale or repeated use. Artificial viruses, although currently less efficient than biological vectors, show increasing promise of being the safer solution ("Targeted Gene Transfer into Hepatoma Cells with Lipopolyamine-Condensed DNA Particles Presenting Galactose Ligands: A Stage...

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Source: Cancer Weekly (1995-03-27)

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