"Mobilization of Hematopoietic Progenitors into the Blood: Mechanisms, Regimens and Outcomes."

According to an abstract submitted by the author to the New York Academy of Sciences conference Bone Marrow Transplantation in the 90's: Into the 21st Century, held March 15-18, 1995, "There are numerous reports in the literature of regimens for 'mobilizing' peripheral blood stem cells (PBSC). These regimens fall into two types, chemotherapy ± hematopoietic growth factors and growth factors alone. The objective and outcome of these regimens is increasing circulating hematopoietic progenitors. The mechanism by which this occurs is wholly unknown. Possibilities include local overcrowding of marrow stroma, induction of chemotactic factor release, expansion of hematopoietic...

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