Published in Cancer Weekly, June 19th, 1995
Tumor-associated Ags (TAA) have been identified that are recognized by CD8 T cells in both murine and human tumor cells. In some cases, CTL cell lines specifically recognizing these TAA are able to induce cancer regression in patients with disseminated metastases.
"With genes encoding relevant TAA now in hand, targeted, Ag-specific vaccines for cancer therapy are being developed," researcher Vincenzo Bronte and colleagues wrote ("IL-2 Enhances the Function of...
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