Published in Cancer Weekly, July 24th, 1995
Previous research has shown that when the CEA gene is placed into vaccinia virus, the recombinant vaccine (rV-CEA) can elicit T-cell responses in animal models. However, experimental animal models have extremely limited extrapolation to potential human immune T-cell responses.
The previous animal models have demonstrated that rV-CEA can infect mammalian cells in vivo to such a level as to induce immune responses and demonstrated the lack of...
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