Published in Cancer Weekly, August 7th, 1995
Recent studies indicate that an increasing proportion of genital HPV infections are subclinical or latent. Routine cytologic and colposcopy exams may not detect latent infections and misdiagnosis is likely. Current DNA detection assays are also limited in that they detect only current infections.
Kurt Heim et al. sought to develop a serologic assay that could evaluate prior virus exposure, detect significant systemic immunologic response to viral infection and could be done in most clinical...
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