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Cancer Vaccines

Technique Topples Barriers: Micrometastases Now Culturable for Vaccines

Published in Cancer Weekly, August 14th, 1995

A recently developed technique now allows researchers to culture the minute amounts of micrometastases available for the development of genetically modified, autologous tumor cell vaccines.

Microscopic metastases are heterogenous cancer cells that have not yet gained the fully autonomous growth potential of mature metastatic cancer. At this stage, these cancer cells are more vulnerable to the patient's intact immune system and are at an idyllic stage for cancer vaccines to be most effective.

Up to this point, it has been extremely difficult to identify such small quantities of cancer cells, much less culture them for the development of autologous...

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