Biotechnology

Future Anti-Cancer Therapeutics Revolve Around Gene Therapy Approaches

Published in Cancer Weekly, August 28th, 1995

Certain gene therapy strategies aimed as cancer treatments are cell specific, efficient, and have fewer side effects than conventional anti-cancer reagents, researchers show.

Biotechnological advances have produced the ability to derive specific recognition domains from monoclonal antibodies (mAb). By recombining variable regions of light and heavy chains, and integrating them into single polypeptides, researchers can use single-chain antibody (Ab) derivatives for specific targeting purposes.

Winfried Wels et al. have developed a fusion protein which is capable of recognizing the ErbB-2 receptor which is overproduced in many adenocarcinomas of the...

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Source: Cancer Weekly (1995-08-28)

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