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Pathogenesis

"Molecular Pathogenesis of AIDS-Associated Non-Hodgkin's Lymphoma."

Published in Cancer Weekly, August 28th, 1995

According to an abstract submitted by the author to the 19th International Congress of Chemotherapy, held July 16-21, 1995, in Montreal, Quebec, Canada, "The AIDS associated lymphomas can be divided into the Burkitt's like subcategory and the large cell lymphomas. The large cell lymphomas represent a complex set of disease processes and are almost equally divided into monoclonal and polyclonal lymphoproliferations. Patients with polyclonal lymphoma (PCL) with greater than 200 CD4 cells per mm3 have a substantially longer survival than patients in other molecular subcategories suggesting a unique pathogenetic process. In depth molecular analysis of PCL revealed a monoclonal...

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