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CBL Protein

Roundworm Protein Similar to Human Cancer Protein

Published in Cancer Weekly, September 4th, 1995

A team of biologists has found a striking similarity between a protein found in roundworms and a common but puzzling protein in humans that is sometimes involved in the growth of cancer.

This link, reported in the August 25, 1995, issue of the journal Science, will help scientists who study human cancer genes direct their research in more promising directions.

The human protein, called CBL - pronounced "sibyl" - was discovered by Wallace Langdon of the University of Western Australia, and is important to the study of cancer in people because a mutant form of CBL promotes the growth of cancer. Scientists already knew that CBL, in either a normal or a...

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