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Prostate Cancer

Findings May Impact Treatment Options for Men with Cancer

Published in Cancer Weekly, September 4th, 1995

The following was released by the Barbara Ann Karmanos Cancer Institute, Detroit, Michigan:

Physicians may soon be able to tell which of their patients with prostate cancer need aggressive treatment.

Researchers at Detroit's Barbara Ann Karmanos Cancer Institute have isolated a potential marker for determining the aggressiveness of human prostate cancer. Their work, published in the August [1995] issue of Urology, found that elevated levels of 12-LOX, an enzyme, may indicate poor prognosis.

"We found that tumors with high 12-LOX expression are likely to have high metastatic potential or are locally advanced tumors," said David...

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