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MACS Study Supports New Theories of AIDS Pathogenesis

Published in Cancer Weekly, October 9th, 1995

AIDS is the result of extensive HIV replication and is not caused by antigenic exhaustion or self-destruction of the immune system, clinical data suggest.

The loss of CD4⁺ T lymphocytes that characterizes AIDS is a phenomenon that researchers have struggled to explain since the dawn of the AIDS epidemic. But the recent availability of tests capable of measuring the amount of HIV in the blood and within infected cells has led to new insights.

These insights, however, are based on studies with patients seen only over a brief period of time. To study the impact of HIV genetic diversity and viral burden, Northwestern University researchers...

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Source: Cancer Weekly (1995-10-09)

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