Published in Cancer Weekly, October 9th, 1995
In vivo gene deliver via adenoviral vectors has been shown to have high therapeutic efficacy. However, the answer to the potential injurious effects of this treatment modality had not been fully answered with previous research.
Kenneth E. Drazan et al. examined liver function and markers of cell injury following adenovirus-mediated gene transfer in a rat model of sham orthotopic liver transplantation ("Hepatic Function is Preserved Following Liver-Directed, Adenovirus-Mediated Gene Transfer," Journal of...
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