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Opportunistic Infections (Kaposi's Sarcoma)

Specific Herpesvirus Associated with KS

Published in Cancer Weekly, October 16th, 1995

The presence of Kaposi's sarcoma-associated herpesvirus in the blood of HIV infected patients with the opportunistic infection is further evidence of its causative role, according to a report from the United Kingdom.

It has long been believed that Kaposi's sarcoma (KS) is sexually transmitted in HIV infected persons, and several candidate infectious agents have been suggested. DNA sequences of a new herpesvirus, known as KS-associated herpesvirus (KSHV), were recently identified in a large majority of AIDS-associated KS lesions.

"We and others have shown that KSHV is also found in most cases of HIV negative KS, including those of Mediterranean and...

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