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Results of LGD1069 Used To Treat Kaposi's Sarcoma Presented

Published in Cancer Weekly, October 16th, 1995

Ligand Pharmaceuticals Inc., San Francisco, California, announced interim results of controlled Phase I/IIb human clinical trials indicating that Targretin Topical (LGD1069) induced a partial or complete response in one or more treated lesions in 52 percent of 23 patients with AIDS-related Kaposi's sarcoma (KS) evaluated to date by AIDS Clinical Trial Group criteria.

Data were presented on the first 23 of 51 patients enrolled in the multicenter trial as of September 15, 1995. These patients had received treatment for at least two months with Targretin Topical (LGD1069), a compound discovered by Ligand scientists which selectively activates a subclass of retinoid...

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