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Treatment IND Filed for Gliadel To Treat Malignant Glioma

Published in Cancer Weekly, October 16th, 1995

Guilford Pharmaceuticals Inc., Baltimore, Maryland, announced that it has submitted to the U.S. Food and Drug Administration (FDA) a treatment Investigational New Drug (IND) application for Gliadel.

Gliadel is a biodegradable polymer implant which is being developed by Guilford for the treatment of malignant glioma, the most common and rapidly fatal type of brain cancer. Gliadel polymer implants are small white wafers which are left in the surgical cavities created when a brain tumor is removed. As the wafer slowly erodes in the brain, it releases the cancer chemotherapeutic drug carmustine (BCNU) directly to the tumor site in high concentrations over an extended...

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