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Diagnostics (PSA)

"The Value of Prostate Specific Antigen in Early Diagnosis of Prostate Cancer: The Study of Men Born in 1913."

Published in Cancer Weekly, October 23rd, 1995

According to the authors' abstract of an article published in Journal of Urology, "Purpose: We attempt to elucidate the performance of serum prostate specific antigen (PSA) as a screening test for prostate cancer. Materials and Methods: We analyzed sera stored since 1980 in a nested case-control study. Results: The 36 patients with prostate cancer had a markedly greater mean serum PSA level than did 68 subjects without cancer (22.71 versus 2.67, respectively, P<0.0001). Among the controls 24% had a serum PSA of greater than 4.0 (mu)g/L. A serum PSA value exceeding 4.0 (mu)g/L. in 1980 was associated with a 20-fold excess risk of cancer between 1981...

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