Cancer Weekly
Welcome to NewsRx!
Learn more about a six-week, no-risk free trial of Cancer Weekly
We're a pay-per-view site for premium content. If you'd like to purchase this article, it's only $3.00.
Cancer Gene Therapy
"p53 Gene Therapy in a Rat Model of Hepatocellular Carcinoma."
November 20th, 1995
According to an abstract submitted by the authors to the 4th International Conference on Gene Therapy of Cancer, held November 9-11, 1995, in San Diego, California, "Alterations in the p53 tumor suppressor gene are frequent in human liver malignancies, including primary hepatocellular carcinoma (HCC) and metastatic colorectal cancer. A recombinant adenovirus encoding wildtype human p53 has been developed to deliver p53, and its anti-tumor effects have been demonstrated using in vitro and in vivo models of human cancer. Because of the affinity of adenovirus for hepatocytes after systemic administration and the unique vascular supply of liver malignancies, an initial...
Source: Cancer Weekly (1995-11-20)
|
|
Advertisement |
|
|
