Genetics (Breast Cancer)

Mutations in P53 Gene Predict Need for Aggressive Cancer Treatment

Published in Cancer Weekly, February 19th, 1996

A study has found that the presence of mutations in the p53 tumor-suppressor gene identifies breast cancer patients at high risk of recurrence of the disease and death following initial treatment.

If the results are confirmed, physicians are predicted to have a method for identifying otherwise unrecognized high-risk breast cancer patients who could benefit from additional treatment following surgery.

The study was led by City of Hope Executive Vice President for Medical and Scientific Affairs John S. Kovach, M.D., while at the Mayo Clinic in Rochester, Minnesota, and Mayo Clinic Medical Geneticist and Molecular Biologist Steve S. Sommer, M.D., Ph.D. ...

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Source: Cancer Weekly (1996-02-19)

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