"HLA2-Binding Peptides Identified in All the HTLV-I Proteins and in the Principal Neutralizing Domain of the Envelope."

According to an abstract submitted by the authors to the 7th International Conference on Human Retrovirology, held October 17-21, 1995, in Paris, France, "The human T-cell leukemia virus (HTLV-I) is the etiologic agent of adult T cell leukemia, tropical spastic paraparesis and other clinical disorders for which no treatment is available so far. The development of an anti-HTLV-I vaccine is therefore an important issue. In order to identify potential CTL epitopes in the HTLV-I virus, we have selected in all the viral proteins, peptides containing anchor residues required for association to HLA-A2 molecules, the most frequent among human populations. Each peptide was tested in two assembly...

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