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Kaposi's sarcoma (Therapy)

"Randomized Cross-Over Comparison of Liposomal Daunorubicin Versus Observation for Early Kaposi's sarcoma."

Published in Cancer Weekly, June 17th, 1996

According to the authors' abstract of an article published in AIDS, "Objectives: To evaluate single-agent liposomal daunorubicin chemotherapy in the management of early HIV-related Kaposi's sarcoma (KS). Design: Randomized cross-over comparison of liposomal daunorubicin versus observation. Setting: Study conducted at single site in tertiary referral HIV unit. Patients: Twenty-nine HIV-seropositive men with <20 cutaneous KS, no visceral involvement and CD4 cell counts < 400x106/L were randomized. Adequate haematological, hepatic and renal function was required for entry. A left ventricular ejection fraction of >45% was necessary...

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