Antisense Technology
TGF-(beta) Antisense Gene Therapy Shows Promise Against Glioblastoma Multiform
Published in Cancer Weekly, July 15th, 1996
The rat 9L gliosarcoma is a good animal model for human glioblastoma multiforme (GBM) as it secretes transforming growth factor-(beta) (TGF-(beta)) which suppresses T-cell activation just like GBM in humans.
H. Fakhrai et al. presented data at the joint meeting of the American Society for Biochemistry and Molecular Biology, the American Society for Investigative Pathology, and the American Association of Immunologists, held June 2-6, 1996, in New Orleans, Louisiana, which showed that...
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Source: Cancer Weekly (1996-07-15)
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