Immunology (HIV)
"CD8 T Lymphocyte-Mediated Suppression of HIV-1 LTR-Mediated Transcription Shows No Correlation with Clinical Stage of Disease or Health Status."
Published in Cancer Weekly, July 22nd, 1996
According to an abstract submitted by the authors to the 11th International Conference on AIDS, held July 7-12, 1996, in Vancouver, British Columbia, "Objectives: CD8+ T lymphocytes of HIV-1 infected individuals efficiently suppress HIV-1 replication in CD4+ T cells and this suppression has been shown to correlate with high CD4+ T cell counts and lack of disease progression. This study examines the transcriptional control of HIV-1 LTR-mediated expression by CD8+ T cells and compares this activity with chemokine production by CD8+ cells and with clinical stage of disease. Methods: Human Jurkat T cells were...
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Source: Cancer Weekly (1996-07-22)
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