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KSHV

"Seroconversion to Antibodies Against Kaposi's sarcoma-Associated Herpesvirus-Related Latent Nuclear Antigens before the Development of Kaposi's sarcoma."

Published in Cancer Weekly, September 9th, 1996

According to the authors' abstract of an article published in New England Journal of Medicine, "Background: If Kaposi's sarcoma-associated herpesvirus (KSHV) is the cause of Kaposi's sarcoma, serologic evidence of infection should be present in patients before the disease develops. Methods: Using an immunoblot assay for two latent nuclear antigens of KSHV, we tested serum samples from homosexual male patients with the acquired immunodeficiency syndrome (AIDS) with and without Kaposi's sarcoma, HIV-infected men with hemophilia, HIV-seronegative blood donors, and HIV-seronegative patients with high titers of antibodies against Epstein-Barr virus (EBV). Serial serum...

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