Human Papillomavirus (Screening)

Method Studied To Improve Cancer Detection After Abnormal Pap Smear

Published in Cancer Weekly, September 30th, 1996

Twenty to 40 percent of all pap smears receive a false negative report, lessening the chance of early detection of cervical lesions.

In a study released in the September 1996 issue of Gynecologic Oncology, physicians used Hybrid Capture - technology that can reliably detect human papillomavirus (HPV) infection - on a population of women who had already received abnormal pap smears. HPV infection can be associated with 93 percent of all cervical cancer cases. The researchers compared these "molecular" findings with the diagnostic gold standard, the cervix biopsy.

The U.S. Food and Drug Administration (FDA)-approved Hybrid Capture test found every...

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Source: Cancer Weekly (1996-09-30)

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