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KSHV

"Antibodies to Human Herpesvirus Type 8 in the General Population and in Kaposi's Sarcoma Patients."

Published in Cancer Weekly, November 4th, 1996

According to the authors' abstract of an article published in Lancet, "Background: Much of the evidence that human herpesvirus type 8 (HHV-8) is associated with Kaposi's sarcoma (KS) has come from molecular studies of HHV-8 DNA. Seroepidemiological studies have been hampered by the lack of a reliable assay. Methods: The serological data reported here were obtained by means of a mouse monoclonal antibody-enhanced immunofluorescence assay for antibodies to lytic and latent HHV-8 antigens. 1435 single samples of serum (or plasma) from many different disease groups and parts of the world were assayed. Findings All patients with African endemic KS and 96% of American...

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