Breast Cancer (Genetics)

Genetics: Why Some Women Smokers Develop Cancer and Others Don't

Published in Cancer Weekly, November 25th, 1996

The answer to the question of whether smoking increases a woman's risk of developing breast cancer may lie in her genes, researchers at the University at Buffalo (UB) and the National Cancer Institute have found.

Results of their study, the first to consider genetic variability as a factor in a person's breast-cancer susceptibility to the carcinogens in cigarette smoke, was published in the November 13, 1996, issue of the Journal of the American Medical Association (JAMA).

The results showed that postmenopausal women born with the slow-acting gene for N-acetyltransferase (NAT2), an enzyme known to detoxify carcinogenic compounds in cigarette smoke,...

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Source: Cancer Weekly (1996-11-25)

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