Published in Cancer Weekly, February 17th, 1997
Potential avenues for gene therapy include the specific targeting of effector genes to cancer cells, including distant metastatic sites. As a first step toward this goal, William M. Siders and colleagues from the U.S. National Cancer Institute-Frederick Cancer Research and Development Center tested the ability of the transcriptional regulatory elements of the mouse and human tyrosinase genes to promote high levels of pigment cell-specific transcription ("Transcriptional Targeting of...
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