Monoclonal Antibodies

Transgenic Production of Antibodies Announced

Published in Cancer Weekly, February 24th, 1997

Genzyme Transgenics Corp., Framingham, Massachusetts, announced that it has successfully demonstrated high level expression of a therapeutic monoclonal antibody in the milk of transgenic goats and that antigen binding levels are equivalent to material produced using conventional, cell culture technology.

The data were announced at the Therapeutic Transgenics Conference, held in West Palm Beach, Florida, where the company also announced that it has demonstrated high-efficiency purification results in a second monoclonal antibody, using a process that has broad application to other antibodies.

The expression results and verification of binding quality...

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Source: Cancer Weekly (1997-02-24)

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