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Kaposi's Sarcoma

"Hormones in the Pathogenesis and Treatment of KS."

Published in Cancer Weekly, April 14th, 1997

According to an abstract submitted by the author to the 3rd Conference on Retroviruses and Opportunistic Infections, held January 28 - February 1, 1997, in Washington, DC, "Kaposi's sarcoma (KS) develops in a variety of clinical settings and is the most common tumor seen in patients with HIV infection. KS develops most commonly in men compared to women (15:1) regardless of the clinical setting. It thus appears that sex hormones play a role in the pathogenesis of this disease. However the lack of sex hormone receptors in KS tissues argue against the direct effect of these hormones. Metabolic products of sex hormones which do not bind the receptors may have direct effects and will be...

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