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Cancer Gene Therapy (Immunotherapy)

IL-2 Transduced Tumor Cells Effective Against Pancreatic Cancer

Published in Cancer Weekly, April 14th, 1997

Specific active immunotherapy using interleukin-2 (IL-2) gene-transduced tumor cells inhibits established pancreatic cancer in a murine model.

Although scientific advances have been made in several cancer treatment areas, the survival of patients with pancreatic cancer of exocrine origin has changed relatively little in the past 30 years. Unfortunately, 90 percent of pancreatic cancer patients are diagnosed as unresectable with metastases to regional lymph nodes, the liver and peritoneal surfaces. Even in patients who are surgically resectable, median survival does not exceed two years, and the five year survival rate is a dismal 15-25 percent. New and innovative...

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