Liposomes
"Interleukin-2 Liposome Inhalation Therapy Is Safe and Effective for Dogs with Spontaneous Pulmonary Metastases."
Published in Cancer Weekly, May 5th, 1997
According to the authors' abstract of an article published in Cancer, "Background: Systemic in vivo toxicity of interleukin-2 (IL-2) has been problematic. Antineoplastic activity of IL-2 has been modest. The authors have previously demonstrated the biologic activity and safety of aerosols of IL-2 liposomes in normal dogs. They now report objective regression of naturally occurring pulmonary metastases in dogs after 1 month of nebulized IL-2 liposome therapy. Methods: Dogs with pulmonary metastases (n = 7) and primary lung carcinoma (n = 2) were treated with aerosols of IL-2 liposomes. Response to therapy was monitored with serial chest radiographs. Effector...
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Source: Cancer Weekly (1997-05-05)
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