Gene Discovery

NIH Team Discovers Endocrine Tumor Gene

Published in Cancer Weekly, May 5th, 1997

A team of scientists at the National Institutes of Health (NIH) has identified a gene that can cause multiple benign tumors of the parathyroid and pituitary glands, as well as islet cell tumors leading to pancreatic cancer.

Their discovery of the gene for multiple endocrine neoplasia, type 1 (MEN1), is reported in the April 18 issue of the journal Science.

As a result of the discovery, doctors will soon be able to screen families at risk for MEN1 more easily and eliminate periodic blood tests for those with normal MEN1 genes. They hope to learn from MEN1 and its protein product, called menin, how endocrine tumors and cancers grow. The discovery...

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Source: Cancer Weekly (1997-05-05)

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