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Kaposi's sarcoma (KSHV)

"Infection with AIDS-Related Herpesviruses in Human Immunodeficiency Virus-Negative Infants and Endemic Childhood Kaposi's sarcoma in Africa."

Published in Cancer Weekly, May 19th, 1997

According to the authors' abstract of an article published in Journal of General Virology, "Novel herpesviruses have been described recently. These include human herpesviruses 6, 7 and 8 (HHV-6, -7, -8). HHV-6 has at least two strain groups, variants A and B. The B strains are predominant in the West and can account for over 97% of infections in infants. In contrast, the A strains are rare and the few well-characterized isolates have been from adult African AIDS patients. It is not clear whether the HHV-6 variant A strains are AIDS-related and/or whether they can also be acquired as childhood infections and may reactivate later during adulthood. What contribution geographical...

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