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Cancer Vaccines
"Cell-Free Tumor Antigen Peptide-Based Cancer Vaccines."
May 26th, 1997
According to the authors' abstract of an article published in Proceedings of the National Academy of Sciences of the United States of America, "The central role that tumor antigen-derived peptides play in induction of antitumor immunity makes them ideal candidates for peptide-based cancer vaccines. We have demonstrated that 'transloading' is an efficient strategy for importing short peptide ligands into antigen-presenting cells in vitro. Postulating that the transloading procedure might effect peptide uptake by antigen-presenting cells in vivo as well, we tested this approach for the generation of peptide-based cancer vaccines. In the P815 mastocytoma system, we vaccinated mice by s.c....
Source: Cancer Weekly (1997-05-26)
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