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Cancer Weekly

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Kaposi's sarcoma (KSHV)



"Identification of Two Homologs of the Kaposi's sarcoma-Associated Herpesvirus (Human Herpesvirus 8) in Retroperitoneal Fibromatosis of Different Macaque Species."



May 26th, 1997

According to the authors' abstract of an article published in Journal of Virology, "Simian retroperitoneal fibromatosis (RF) is a vascular fibroproliferative neoplasm which has many morphological and histological similarities to human Kaposi's sarcoma (KS). Like epidemic KS in AIDS patients, RF is highly associated with an immunodeficiency syndrome (simian acquired immunodeficiency syndrome [SAIDS]) caused by a retrovirus infection. Recently, a new gammaherpesvirus, called Kaposi's sarcoma-associated herpesvirus (KSHV) or human herpesvirus 8 (HHV8), has been identified in KS tumors, suggesting that KS has a viral etiology. Our previous experimental transmission studies and...


Source: Cancer Weekly (1997-05-26)

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