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Prostate Cancer (Diagnostics)
"Novel Bispecific Immunoprobe for Rapid and Sensitive Detection of Prostate-Specific Antigen."
May 26th, 1997
According to the authors' abstract of an article published in Clinical Chemistry, "Prostate-specific antigen (PSA) is one of the most useful tumor markers for the screening and follow-up of prostate cancer. Bispecific monoclonal antibodies (bsMAbs) are unique immunoprobes that incorporate two different binding sites in the same antibody molecule. This antibody designing can bring important advantages in the development of new immunoassays. We have developed a new hybrid hybridoma that secretes bsMAb anti-PSAxanti-horseradish peroxidase. This bsMAb has shown rapid kinetics and an excellent detection limit in a sandwich single-step assay with a total incubation time of 15 min and a 5-min...
Source: Cancer Weekly (1997-05-26)
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