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Cancer Weekly

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Pathogenesis (GBV-C/HGV)



"Genotypes and Quantification of GB Virus C/Hepatitis G Virus."



May 26th, 1997

According to an abstract submitted by the authors to the 4th International Meeting on Hepatitis C Virus and Related Viruses, Molecular Virology and Pathogenesis, held March 6-10, 1997, in Kyoto, Japan, "To determine the genetic heterogeneity of GBV-C and hepatitis G virus (HGV), 2,918 samples from 37 countries were screened to be positive for HGV RNA by RT-PCR. After the determination of nucleotide sequences in 5'UTR and NS5 region of HGV RNA among the samples with HGV RNA, we analyzed these sequences by the 6-parameter and the Neighbor-Joining method. With the alignment to all the sequences, a restriction fragment length polymorphism (RFLP) assay was developed. Moreover, serum...


Source: Cancer Weekly (1997-05-26)

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