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Cancer Weekly

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Adenomatous Polyposis Coli



Phase III Trials of FGN-1 Begin for Precancerous Colon Polyp Therapy



May 26th, 1997

Cell Pathways Inc., West Conshohocken, Pennsylvania, announced the start of a multi-national Phase III trial of its lead investigational drug, FGN-1, as preventative therapy for precancerous colon polyps in patients with adenomatous polyposis coli, (APC; also known as familial adenomatous polyposis, FAP).

Colon polyps are often precursors to colorectal cancers.

Patients with APC, a relatively rare inherited disease, form large numbers of colon polyps and face a high risk of colon cancer at an early age. Colon polyps also occur sporadically, but repeatedly, in a large portion of the general U.S. population. As these lesions are known to precede the...


Source: Cancer Weekly (1997-05-26)

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