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Cancer Therapy

Phase I Results with Onyx-015 Updated

Published in Cancer Weekly, July 28th, 1997

Onyx Pharmaceuticals, Richmond, California, updated the results from a Phase I human safety study of its Onyx-015 anticancer virus in patients with recurrent and refractory head and neck tumors.

The company also announced that it has initiated a Phase II efficacy trial with Onyx-015 in that same indication and is planning to start Phase II testing of the virus in combination with chemotherapy.

In a presentation made at the Montgomery Securities Healthcare Conference, held in New York, Hollings C. Renton, Onyx, said that treatment with Onyx-015 was well-tolerated by all of the 32 patients completing the trial, and investigators observed no...

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