Virology

New Understanding of HHV-8 Mode of Action may Help Fight HIV

Published in Cancer Weekly, September 29th, 1997

A herpes virus that causes an AIDS associated cancer may act as a kind of molecular spy against its own kind, offering valuable information on how to fight HIV, researchers said.

They said human herpesvirus 8 (HHV-8) had surrendered secrets about how it steals a gene from its human patient and uses it to invade cells in an act of "molecular piracy."

Thue Schwartz, University of Copenhagen, Denmark, and a team of international colleagues, working with Glaxo-Wellcome, found the virus produces vMIP-II, a protein that looks like a chemokine.

Chemokines are signalling chemicals involved in immune response and known to be important to...

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Source: Cancer Weekly (1997-09-29)

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