Endometrial Cancer

Genetic Link to Uterine Cancer Found in PTEN Gene Mutation

Published in Cancer Weekly, October 20th, 1997

Researchers said they had found a new genetic link to cancer of the womb, and said the gene may be linked to other cancers as well.

The researchers, at the University of Maryland School of Medicine in Baltimore, Maryland, and Tohoku University School of Medicine in Japan, found the mutation in more than half the women they studied who had cancers of the endometrium.

Reporting in the October 1, 1997, issue of the journal Nature Genetics, they said 55 percent of 38 different endometrial tumors they tested had a mutation in the PTEN gene.

They said the PTEN gene (short for phosphatase and tensin homologue deleted on chromosome 10)...

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Source: Cancer Weekly (1997-10-20)

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