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Development of BCX-34 Topical Cream Formulation Discontinued

Published in Cancer Weekly, October 20th, 1997

BioCryst Pharmaceuticals, Inc., Birmingham, Alabama announced preliminary Phase III trial data for two trials with a topical cream formulation of the company's lead drug candidate, BCX-34.

Initial findings from a Phase III clinical study for the treatment of psoriasis and a Phase III trial to treat cutaneous T-cell lymphoma (CTCL) demonstrated no statistical differences in the achievement of study endpoints between BCX-34-treated and placebo groups.

The primary endpoint for the Company's Phase III CTCL trial was a 50 percent or greater decrease in body surface area covered with patch and plaque cancerous lesions during the six-month course of...

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