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Cancer Vaccines
GM-CSF-Transduced Tumor Vaccine Effect in Murine Leukemia Model
November 24th, 1997
A granulocyte-macrophage colony-stimulating factor (GM-CSF)-transduced tumor vaccine elicits immunological responses in a murine leukemia model. Several studies have used GM-CSF-transduced tumor vaccines in solid tumor animal models (C.A. Armstrong et al., Cancer Research 1996;56:2191-98; H. Waikimoto et al., Cancer Research 1996;56:1828-33; and others). Chia-Ling Hsieh and colleagues from the National Taiwan University and Hospital, Taiwan, however, investigated the therapeutic effects of a GM-CSF-transduced vaccine in a murine leukemia model ("Regression of Established Mouse Leukemia by GM-CSF-Transduced Tumor Vaccine: Implications for Cytotoxic T Lymphocyte...
Source: Cancer Weekly (1997-11-24)
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