Cancer Weekly
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Metastasis
Cell-Suicide Gene Linked To Cancer Spread
November 24th, 1997
A Weizmann Institute of Science study reported in the November 13, 1997, issue of Nature provides new evidence for a recent theory about the development of metastasis. According to this theory, one of the factors contributing to metastasis - the spread of cancer from the site of the primary tumor to other body organs - is a loss of a mechanism by which cells "commit suicide." In the new study, Weizmann researchers in Rehovot, Israel, demonstrated that a cell-suicide gene called DAP-kinase can prevent metastasis. This finding suggests that a loss or malfunction of this gene allows metastasis to develop. "In our experiment, we have...
Source: Cancer Weekly (1997-11-24)
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