Kaposi's Sarcoma
V-Cyclin D mRNA Is Predominant in Tumor Cells
Published in Cancer Weekly, February 9th, 1998
"Expression of v-cyclin D protein may be involved in the pathogenesis of Kaposi's sarcoma by promoting cell proliferation," wrote Monica A. Davis, Vanderbilt University, Nashville, Tennessee, and colleagues ("Expression of Human Herpesvirus 8-Encoded Cyclin D in Kaposi's Sarcoma Spindle Cells," Journal of the National Cancer Institute, December 17, 1997;89:1868-1874).
The protein may represent a target for therapeutic intervention, the authors indicated.
Davis et al. isolated a human herpesvirus-8 (HHV-8) complementary DNA clone encoding the viral homologue of...
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Source: Cancer Weekly (1998-02-09)
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