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Disease Associations

"Human Herpesvirus 8 in Patients with Multiple Myeloma."

Published in Cancer Weekly, March 23rd, 1998

According to an abstract submitted by the authors to the 39th Annual Meeting of the American Society of Hematology, held December 5-9, 1997, in San Diego, California, "Human herpesvirus 8 (HHV-8), also known as Kaposi's sarcoma-associated herpesvirus, has been implicated in a variety of disorders including Kaposi's sarcoma, primary effusion lymphomas and multicentric Castleman's disease. An HHV-8 protein has been described with close homology to human IL-6, a cytokine with stimulatory activity on plasma cells and that is secreted at high levels by stromal cells from patients with multiple myeloma (Science, 274:1739, 1996). Bone marrow stromal cells with a dendritic cell phenotype grown...

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