Disease Markers

Drug Ineffective Against Progressive Multifocal Leukoencephalopathy

Published in Cancer Weekly, May 18th, 1998

Tests show that the anti-cancer drug cytarabine is not effective for treating AIDS patients with progressive multifocal leukoencephalopathy (PML), according to a report in the May 6, 1998 issue of The New England Journal of Medicine.

Cytarabine, sold under the brand name Cytosar-U by Pharmacia & UpJohn, has been prescribed for people with PML. The once-rare condition makes brain cells deteriorate, causes vision problems, confusion and muscle weakness.

The condition strikes about 4 percent of patients with AIDS, typically killing them in about three months. There is no other effective therapy.

To test cytarabine, Colin D. Hall,...

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Source: Cancer Weekly (1998-05-18)

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